1. Unexplained Fatigue and Mental Fog
When renal filtering capacity drops, metabolic waste products build up in your bloodstream—a condition known as uremia. This accumulation of toxins can leave you feeling chronically exhausted or unable to concentrate. Furthermore, healthy kidneys produce erythropoietin, a hormone that signals your bone marrow to manufacture red blood cells. As functional kidney tissue declines, erythropoietin production drops, leading to mild anemia that compounds feelings of lethargy.
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